The honest guide to NAD+, sermorelin & B12
You’ve seen these three promoted with very big words. Here’s what they actually are, what the research does and doesn’t show, and what each one costs — so you can decide with clear eyes. A medical provider licensed in your state reviews your health history and decides whether any of them is appropriate for you. Sometimes the answer is no, and we’d rather tell you that than sell you something.
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If you read nothing else on this page, read this.
Nobody can honestly promise you that a vial will slow aging, extend your life, or transform your energy — because the evidence to promise it does not exist, and nobody selling these products has it. What's actually known is narrower: small human studies show NAD+ can raise blood levels, but whether that changes how you feel has not been established in rigorous human trials; sermorelin has no FDA-approved product on the market today; and extra B12 helps mainly when you're genuinely deficient. All three are compounded and not FDA-approved. Sometimes the most valuable thing here is a no. Take the free health history — a medical provider licensed in your state tells you honestly whether any of this fits. Individual results vary.
What we won’t promise you
This category of medicine attracts bigger promises than almost any other — that a vial can slow aging, extend your life, recharge your cells, or transform your energy. We won’t tell you any of that, because the evidence to promise it does not exist. Nobody selling these products has that evidence. The difference is whether they tell you.
Here’s what we will do instead: describe each option accurately, show you the honest state of the research — including where it’s thin — post every price, and put a licensed medical provider between you and any prescription. If one of these fits your health picture, your provider will say so. If it doesn’t, they’ll say that too.
How this works
Complete your online visit. A health history you fill out on your own time — your initial visit is asynchronous, so there’s no appointment to book.
A medical provider licensed in your state reviews it. If an option is appropriate for you, they prescribe it. If not, they decline — and you’re refunded in full.
First refill review at 3–4 weeks. Your provider checks in on how it’s going before your first refill.
Then refills move to a 12-week rhythm, with your provider continuing to oversee your plan.
Every option, explained honestly
All three are prepared by state-licensed compounding pharmacies and are not FDA-approved. Plans renew every 28 days — 13 cycles per year. 12-week plans are billed once per term; that’s why their per-28-day rate is lower.
NAD+ Injection or Nasal Spray
What it is: Nicotinamide adenine dinucleotide — a coenzyme found in every cell in your body, involved in how cells convert food into usable energy. Prescribed as a self-administered injection or a nasal spray, prepared by a state-licensed compounding pharmacy (not FDA-approved).
What the evidence shows: Small human studies show that supplementing can raise NAD+ levels in the blood. Whether raising those levels changes how you feel, slows any aspect of aging, or improves long-term health has not been established in rigorous human trials — most of the exciting findings so far come from lab and animal studies. That’s the honest state of the science, and your medical provider will discuss it with you.
Sermorelin Injection
What it is: A synthetic fragment of growth-hormone-releasing hormone (GHRH). Rather than injecting growth hormone itself, sermorelin prompts your pituitary gland to release your own. Worth knowing before anyone sells it to you: there is no FDA-approved sermorelin product on the market today — the previously approved version was discontinued by its manufacturer in 2008, and every sermorelin prescription in the US is now compounded.
What the evidence shows: Sermorelin was studied decades ago, mainly as a diagnostic tool and in children with growth-hormone deficiency. Evidence for wellness use in healthy adults is thin — small, short studies without large trials showing benefits you’d notice. Your medical provider weighs that record against your health picture before prescribing anything.
B12 MIC Injection
What it is: Vitamin B12 combined with methionine, inositol, and choline (the “MIC” in the name), as a self-administered injection prepared by a state-licensed compounding pharmacy (not FDA-approved).
What the evidence shows: B12 has one clear, well-established use: correcting a documented B12 deficiency. If your levels are normal, extra B12 has not been shown to add anything — and we won’t suggest otherwise. The MIC blend has a long tradition in weight-management clinics but thin trial evidence behind it. If your medical provider suspects a deficiency or sees a specific reason for it in your health picture, they’ll say so; if not, they won’t prescribe it.
Intro pricing applies to the every-28-days NAD+ and sermorelin plans — $199 your first 4 weeks, then $239 every 28 days. Compounded medications are prepared by state-licensed compounding pharmacies and are not FDA-approved. A medical provider licensed in your state decides whether any option is appropriate for you.
Three rules for reading longevity marketing — including ours
- A mechanism is not an outcome. “Involved in cellular energy metabolism” is a fact about biochemistry, not a promise about how you’ll feel. When copy slides from the first to the second, that’s the trick.
- Animal studies are not human results. Much of what makes this category exciting happened in mice and cell cultures. Human evidence is the bar that matters, and for these options it is thin.
- Raising a level is not the same as feeling different. A number moving on a lab report doesn’t establish a benefit you’d notice. Ask what changed for actual people in actual trials — and how big those trials were.
Hold every brand to these rules. Especially us.
Included with every plan
Already on a weight plan with us?
These same three options can be added to an existing weight plan during a provider review — at the same prices you see here. Nothing on this page costs more as an add-on, and nothing costs less as a standalone. One price, posted.
From the Learn library
Two plain-language guides that go deeper than this page — what the NAD+ evidence really shows, and what B12 and MIC injections honestly are.
What Is NAD+? The Honest Evidence for Women
What NAD+ is, the candid state of the research, and why the compounded versions aren’t FDA-approved.
Read the guide →B12 and MIC Injections: What They Are
B12 helps when you’re deficient — and only then. The honest limits of MIC, with no weight-loss or energy promises.
Read the guide →If it’s not right for you, you deserve to hear that
Complete the free online health history. A medical provider licensed in your state will review it and give you a straight answer — a plan if one fits your health picture, and a no if it doesn’t. Either way, you’ll know more than the marketing told you.
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